Lateral Flow Test and Development Blog
04/09
2020
Diagnostic CRISPR Tools and Techniques
Lateral Flow Assays using Genome Editing Tools
What is CRISPR/Cas?
The CRISPR / Cas system acts as an immune system equivalent that is anchored in the genome of bacteria and archaea. The underlying mechanism protects the organism from phage infections by sequence specific destruction of “unknown” nucleic acids. The CRISPR/Cas-system has the ability to learn, remember and adapt. (1, 2)
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03/27
2020
6 new Articles, referring to the use of CRISPR/Cas and HybriDetect
DNA and RNA Detection with the Help of HybriDetect
New techniques have been developed for the specific detection of DNA or RNA sequences. They all have in common, that they use CRISPR/Cas12 or Cas13. The enzyme recognizes a specific target sequence. After binding to this sequence, its endonuclease activity is activated and it cleaves any reporter sequence. This technique can be easily combined with our Lateral Flow Assay HybriDetect for the visualization of the results.
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03/20
2020
HybriDetect and Temperature Effects
Using higher Temperatures: Part of the NAFLIA Toolbox
Higher Temperatures: Stability aspects and assay Parameters
The general robustness is a characteristic feature of lateral flow devices (LFD’s). Even during longer transports and extreme weather conditions LFD’s remain stable. Temperature is an important factor when it comes to robustness. Therefore our HybriDetect test strips are regularly tested at higher temperatures.
Especially in the development of NALFIA’s (Nucleic Acid Lateral Flow Immunoassays), the temperature can influence the test result significantly. Higher temperatures can also be understood as tool in the assay procedure to achieve certain results. The hybridization of amplificates is classified as particularly interesting. The use of a defined temperature is a crucial parameter to maintain specific hybridizing conditions. read more…
10/08
2019
Our new Website is online!
We are happy to announce the launch of our new Website. We have a new Design, new Content and a new Shop.
The Shop is directly included in our product sites to simplify your ordering process.
New Content to our specific products has been created and the structure on the product pages is improved.
Please visit www.milenia-biotec.de to see all the smaller but impactful changes!
We hope you enjoy our new, more user-friendly Website!
If you have any Feedback, please let us know on LinkedIn or by E-Mail.
08/12
2019
Detecting Viruses
Major Pathogens in Aquaculture
Several investigative techniques have been developed to detect viruses causing severe fish and shrimp diseases. The methods used are LAMP and RPA combined with our Lateral Flow Dipstick (LFD) for DNA Detection: HybriDetect. The addressed viruses cause diseases with a high mortality rate and therefore have a huge economic impact in fish farming industries (1 – 6).
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03/11
2019
Hygiene monitoring in breweries
Results in just 2 hours – Immediate corrective actions possible!
The quality of beer is controlled in breweries at each individual level of the production process. The presence of beer spoilage microorganisms is associated with an elevated risk to beer quality. Microbial contaminations create a negative impact on the taste, the texture and the smell of the final product. Contamination can occur over the entire production process, although the area of the filling machine is the main spot for contamination. For this reason, filling machines are cleaned intensively on a regular basis and the success of the cleaning process is controlled via close hygiene monitoring.
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